Endocrine Abstracts

Fragile bone fractures due to deteriorating bone quality are increased in patients with type 2 diabetes mellitus. This study aimed to measure serum levels of pentosidine and adipocytokines, e.g. adiponectin and leptin, and compare between those biochemical markers and bone mineral density of lumber in patients with type 2 diabetes mellitus. Serum concentration of adiponectin, leptin and pentosidine was measured in 19 type 2 diabetic patients (mean age 65.9+2.3 years) and 13 no...

Rheumatoid arthritis (RA) is a chronic inflammatory disease that results in generalized bone loss and increased fracture risk. Although glucocorticoids are frequently prescribed for the symptomatic management of inflammatory disorders such as RA, extended glucocorticoid exposure is the leading cause of osteoporosis and leaves patients at a high risk of fracture. The aim of this study is to evaluate the efficacy and safety of monthly oral minodronate for the treatment of osteop...